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Inherited Arrhythmia Syndrome

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Familial Arrhythmia Syndrome - An Overview

Did you know that certain heart conditions can be passed down from one generation to the next? Familial (inherited or genetic) arrhythmia syndrome is one such condition that can increase your risk of developing life-threatening conditions like Ventricular Fibrillation, Ventricular Tachycardia or even sudden cardiac death.

The symptoms of familial arrhythmia syndrome may worsen during exercise or emotional stress. If not treated, inherited arrhythmias may cause the heart to stop beating and may result in sudden death. Sometimes you may not experience any symptoms at all, but you may have a family history of sudden deaths. Even healthy individuals are at great risk of sudden cardiac death if they have inherited genetic heart arrhythmia from their parents. These high risks call for a family-centred approach to cardiac care. Here’s where Dr Karthigesan’s expertise makes a difference. His care and guidance play a pivotal role in inherited arrhythmia syndrome diagnosis and treatment.

  • Fainting or syncope
  • Dizziness
  • Seizures
  • Pounding sensation in the chest
  • Feeling of breathlessness
  • Torsades de Pointes: Torsades de Pointes is a severe form of ventricular arrhythmia where the heart's lower chambers beat rapidly and irregularly, creating a twisted pattern on an ECG. This erratic heart rhythm reduces blood output, potentially leading to sudden fainting. In severe cases, extended fainting spells may result in full-body seizures and life-threatening ventricular fibrillation if the rhythm doesn't self-correct.
  • Ventricular Fibrillation: This dangerous condition causes the ventricles to beat abnormally fast, making the heart quiver and cease pumping blood. If Ventricular Fibrillation occurs, a defibrillator should shock your heart back into normalcy. If not, it can result in brain damage and death.
  • Sudden death: A common cause of sudden death in young people who appear to be healthy is familial arrhythmic syndrome.
  • Sudden fainting spells, seizures, and other accidents: Long QT syndrome might be responsible for unexplained deaths in children and young adults.
A female heart expert holding a heart model with virtual heart pulse signals illustrates Familial Arrhythmia care.

Types of Inherited Arrhythmia Syndrome

Familial Arrhythmia Syndrome Treatment

There is nor cure for inherited arrhythmias. However, there is no reason to lose hope because Dr. Karthigesan can put you on the right kind of treatment options depending on the type of Arrhythmia.

Lifestyle changes

Making some long-term changes in your lifestyle can help you prevent sudden cardiac arrest caused due to familial arrhythmia syndrome. Dr. Karthigesan may as you to avoid stressful situations, physical exertion and strenuous exercises.


For inherited arrhythmia syndrome, Dr. Karthigesan may suggest antiarrhythmic medications to regulate your fast heart rate.

Surgery AICD Implantation

In some familial conditions where the risk of cardiac death is relatively high, Dr Karthigesan may suggest you to opt for AICD(Implantable Cardioverter Defibrillator) implantation to safeguard your life.

Left Cardiac Sympathetic Denervation Surgery

Left cardiac sympathetic denervation is a therapeutic solution for individuals facing severe ventricular arrhythmias, particularly catecholaminergic polymorphic ventricular tachycardia (CPVT). Dr. Karthigesan leverages cutting-edge imaging and diagnostic technologies to execute precise interventions, notably benefiting patients with long QT syndrome.
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A Guide to Genetic Heart Arrhythmias

Dr. Karthigesan may suggest the following diagnostic tests to confirm or rule out the possibility of inherited Arrhythmia:

  • Electrocardiogram
  • Holter monitor test
  • Echocardiogram
  • Genetic Testing
  • Extended loop Recorder
  • Insertable loop recorder
Dr. Karthigesan may recommend a genetic test to confirm inherited Arrhythmia. The test is done with your blood samples or cheek swabs. If your test results are positive, he may suggest your family members take the test to confirm the presence of the inherited gene. On the other hand, a negative test result only means that the inherited gene wasn’t detected. But it does not guarantee that you are free of the heart disorder.

You should immediately consult Dr. Karthigesan for a complete cardiac examination and analysis of your heart rhythm. Dr. Karthigesan is a Certified Electrophysiology Specialist (CEPS) and the best physician you can trust to correctly diagnose your condition. 

If diagnosed with inherited hereditary arrhythmia syndrome, Dr. Karthigesan may recommend diagnostic tests for your immediate family members since there is a 50% likelihood of them inheriting the genes. He will also risk-stratify you to diagnose the risk of sudden cardiac death and prescribe recommended medications. If needed, he will suggest device implantations if you belong to the high-risk group.

You may likely have experienced symptoms of genetic heart arrhythmias even before you are aware of your condition. Sometimes you may not experience any symptoms at all. It is important to understand that your outlook depends greatly on how your daily life is affected and what type of genetic mutation you have. In some cases, to avoid sudden cardiac arrest, Dr. Karthigesan may ask you to avoid stressful situations and strenuous physical activities.

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